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Lung India Official publication of Indian Chest Society  
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ORIGINAL ARTICLE
Year : 2008  |  Volume : 25  |  Issue : 3  |  Page : 109-110

Adenosine deaminase (ADA) level in tubercular pleural effusion


1 Department of TB & Chest Diseases, CSM Medical University, Lucknow; M.L.N. Medical College, Allahabad., India
2 Department of Pathology, CSM Medical University, Lucknow; M.L.N. Medical College, Allahabad., India
3 Department of Statistics, CSM Medical University, Lucknow; M.L.N. Medical College, Allahabad, India

Correspondence Address:
S K Verma
Department of Pulmonary Medicine, CSM Medical University, UP, Lucknow- 226 003.
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-2113.44121

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Study objective : To study the value of adenosine deaminase level in tuber­cular pleural effusion. Design: A hospital based observational study. Setting : Out and In patients service of department of Tuberculosis & Chest Diseases, MLN Medical College Allahabad. Patients : 50 consecutive patients of pleural effusion, who were above the age of 12 years, were studied. RESULTS: Pleural fluid adenosine deaminase was more than 36 IU/L (36 to 229.7 IU/L) in tubercular pleural effusion (34 patients). In case of malignancy no. of patients was 08 and pleural fluid adenosine deaminase was more than 18.5 IU/L (18.5 to 87.6 IU/L). While in one case of hypoprotenemiea pleural fluid adenosine deaminase was 8.21 IU/L. If 36 IU/L is taken as cut of limit the sensitiv­ity and specificity of ADA for tuberculosis is 100 % and 77.7 %. More than 100 IU/L was exclusively seen in tubercular pleural effusion. Conclusion: ADA > 100IU/L was observed in TB only.


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