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Lung India Official publication of Indian Chest Society  
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Year : 1982  |  Volume : 1  |  Issue : 1  |  Page : 5-10

Clinical Profile Of Sarcoidosis In India

Correspondence Address:
Samir K Gupta

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Source of Support: None, Conflict of Interest: None

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Till 1981, a total of 75 cases of systemic sarcoidosis has been reported in India. The present paper summarises the clinical profile of all these cases grouped into three series: A (34 from Calcutta), B (24 from Delhi) and C (17, other sources). Clinical presentation and course differed somewhat from that recorded in textbooks and described by Western authors. Fever (81%), Cough (81%), with or without dyspnoea (66%) and loss of weight (63%) were the four most frequent symptoms, while hepato-splenomegaly (73%) and transient tenderness in joints (66%) were the two common signs in series A. Dissociation between extensive radiological changes and clinical signs in chest was remarkable (88%) in the same series. Ocular symptoms, cutaneous signs, (especially orythema nodosum), localised or generalised lymphadenopathy, neurological features like cranial nerve palsy or convulsions e and bone cysts were uncommon in this combined Indian series. Spontaneous resolution or asymptomatic regression (even in cases with bilateral hilar adenopathy) was very in frequent. Follow-up reports, whenever available, showed that patients had frequent relapses, which responded well to steroids but not so well to chlorquine/oxyphenbutazone, given for 10-12 weeks. Sarcoidosis, as seen in India, differs in many ways from the disease, reported from western Countries.

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