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Experience from Baroda (Gujarat State) of studies on different groups of tuberculous patients treated with conventional drugs along with intermittent rifampicin exhibited for durations ranging from 13 to 24 weeks under programme conditions, forms the subject matter of this report. The paper deals with five different studies where twice or once a week rifampicin containing regimens, are found to be 100% effective. In the experience of the author, patient's compliance seems to be relatively high in his part of the country compared to the service programme operating in other areas. Adverse reactions, of an immunological nature to rifampicin, are found to be less than 1% in these series of patients and the total cost is not more than conventional 12-18 months therapy with standard drugs. Relapses appear to be few when patients in the first two studies were followed up over a period of two and a half to four years.
