Source of Support: None, Conflict of Interest: None
Both the radioactive and non-radioactive pollutants in the air can cause cancer in the human lung. Cancer occurrence follows the deposition and retention of pollutants which need be measured accurately. Respiratory parameters affect the deposition and retention patterns of the pollutants in the lung. Several methods are used to produce aerosol particles for determining the deposition fractions in the lung. An index of inhalation risk can be evaluated using the respiratory parameters to assess the likelihood of occurrence of lung cancer in humans. Smoking can be suspected to impair the normal functioning of the lung in which case a carcinogenic pollutant can lodge itself in the lung tissue resulting in an increased dose and facilitate the development of cancer. The present study points out that it is necessary to measure the various respiratory parameters while determining the deposition fraction of aerosol particles in the human lung. Respiratory functioning is an important factor to be considered in explaining the variations noted in the development of cancer among individuals.