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Lung India Official publication of Indian Chest Society  
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Year : 1985  |  Volume : 3  |  Issue : 3  |  Page : 109-113

Inhalant Corticosteroids - A Decade Of Use

Correspondence Address:
Samir K Gupta

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Source of Support: None, Conflict of Interest: None

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Evaluation of inhalant corticosteroids was thought necessary in view of the wide variation of published reports. Beclomethasone dipropionate and betamethasone valerate were evaluated in nonsteroid dependent and steroid-dependent asthmatics separately. In the stubborn cases of non-steroid-dependent asthma, it was found that aerosol and oral steroids were equally effective and that 400μg of beclomethasone was equipotent with 7.5 mg prednisolone. In the cases of true steroid dependent asthmatics good short-term results deteriorated when along follow-up was done after replacement of oral steroids with aerosol forms. In general, chances of total replacement were better in children, in females and in those taking oral steroids at a dose of less than 0.6 mg/kg or 15 mg/day for less than three years. Oral candidiasis was conspicuously absent.

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