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The response of forced expiratory volume to inhaled isoprenaline was studied in 21 patients during the primary episode of tropical pulmonary eosinophilia (TPE), in 13 patients during a relapse of the disease and in 9 patients before and after a course of Diethyl Carbamazine (DEC). Patients with primary presentation were on the whole unresponsive to inhaled isoprenaline whereas the patients with relapse showed significant response; (P<0.02). Pre and Post DEC groups did not reveal any significant differences. Possible reasons for differing airways response in different stages of illness in TPE are discussed.
