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Lung India Official publication of Indian Chest Society  
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Year : 1996  |  Volume : 14  |  Issue : 2  |  Page : 60-65

Clinical Profile Of Bronchial Asthma In Eastern India - A Prospective Analysis Of 7208 Patients

Correspondence Address:
S. K Gupta

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A study to evaluate the clinical profile of bronchial asthma in eastern India was undertaken at Calcutta Medical Research Institute during a period of 25 years (1970-1994). Of the 26826 bronchial asthma patients attended the institute during the period, 7208 patients were studied in detail childhood (3-15 years) asthma was seen in 678 children (9.4%). In young children (3-5 years), boys with asthma outnumbered girls (3:1), while in teenagers (13-15 years) girls had preponderance (2.5:1) over boys. Of the 6530 adult asthmatics, 54.5% were males and 45.5% were females. Clinically extrinsic asthma was seen in 80.5% and intrinsic variety in 12.8%, 34% of adult asthmatics had evidence of recurrent nasal allergy with or without infection by 10th year of the life and this proportion increased to 67.3% by the age of 15 years. Familial atopy was present in 82.1%. Allergy (91.3%) heredity (82.1%), infection with or without preceding nasal allergy (78.3%), sudden temperature change (17.3%) heavy meals at night (15.6%), smoking (11%), psychosomatic factors (7.1%) and household work in women were found to have significant influence on asthma. House dust mite (82.3%) and house dust (77.3%) were the two most common allergens. Food allergy was fairly frequent (70.1%). Allergic bronchopulmonary aspergillosis and nasal polyp – aspirin allergy syndrome were rare. Classical nocturnal asthma (4-6a.m) was seen in 11% while early night attacks (12 midnight – 2 a.m.) were frequent (38.1%). Temporary remission at puberty was seen in 32%, but nasal problems persisted in them. Under diagnosis and under treatment of childhood asthma were common.

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