Home | About us | Editorial Board | Search | Ahead of print | Current Issue | Archives | Instructions | Online submissionContact Us   |  Subscribe   |  Advertise   |  Login  Page layout
Wide layoutNarrow layoutFull screen layout
Lung India Official publication of Indian Chest Society  
  Users Online: 1005   Home Print this page  Email this page Small font size Default font size Increase font size
Year : 1998  |  Volume : 16  |  Issue : 3  |  Page : 113-114

Cholesterol In Pleural Effusions : A Parameter To Distinguish Exudates And Transudates

Correspondence Address:
S Chander

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Forty four consecutive patients of pleural effusion were analyzed for pleural fluid protein, lactate dehydrogenase (LDH) and cholesterol levels. The patients were classified into transudates (n=16) and exudates (n=28) based on the Lights criterion. Pleural fluid cholesterol levels (PCHOL) determined in the transudative and exudative groups were found to be 35.4 ± 6.8 mg/100 ml and 80.3 ± 11.6 mg/100 ml respectively. This difference was found to be statistically significant (p<0.001). Similarly the ratio of pleural fluid to serum cholesterol values (P/SCHOL) was 0.17 ± 0.02 and 0.63 ± 0.09 in the transudative and exudative groups respectively which was also statistically significant (p< 0.001). With a cut off value of 55 mg/l00 ml for pleural fluid cholesterol and 0.3 for P/SCHOL ratio, the number of patients misclassified was one and none respectively, thereby showing that PCHOL and P/SCHOL determinations provide a sensitivity of 96.6% and 100% respectively. It is, therefore, suggested that PCHOL (value of > 50 mg/100 ml and P/SCHOL ratio of > 0.3 might be considered as indicative of exudative pleural effusion.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded131    
    Comments [Add]    

Recommend this journal