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Lung India Official publication of Indian Chest Society  
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Year : 2001  |  Volume : 19  |  Issue : 2  |  Page : 15-17

Diaphragmatic Electrophysiological Studies In Patients Of Respiratory Failure With Difficult Weaning

Correspondence Address:
Puri Sandeep

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Ten patients of acute neuromuscular and no neuromuscular respiratory failure being mechanically ventilated in the respiratory care unit of Department of Medicine of Dayanand Medical College & Hospital, Ludhiana, who were difficult to “wean off” underwent phrenic nerve conduction study and needle electromyography of the diaphragm. Seven out of these ten patients had a neuromuscular type of respiratory failure while three had non neuromuscular causes. Phrenic nerve conduction studies showed reduced amplitude of the diaphragmatic compound muscle action potential (CMAP) in patients with neuromuscular type of respiratory failure. The amplitude of the diaphragmatic CMAP was normal or mildly reduced in patients with neuromuscular type of respiratory failure. Thus, neurophysiological studies can reliably differentiate between.

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