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January-March 2009 Volume 26 | Issue 1
Page Nos. 1-30
Online since Tuesday, January 20, 2009
Accessed 52,625 times.
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EDITORIAL |
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Tuberculosis and sarcoidosis: The continuing enigma |
p. 1 |
Dheeraj Gupta DOI:10.4103/0970-2113.45194 PMID:20165584 |
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FROM THE EDITOR’S DESK |
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The new-look Lung India |
p. 2 |
SK Jindal DOI:10.4103/0970-2113.45195 PMID:20165585 |
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ORIGINAL ARTICLES |
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Sputum smear microscopy in DOTS: Are three samples necessary? An analysis and its implications in tuberculosis control |
p. 3 |
Sukhesh Rao DOI:10.4103/0970-2113.45196 PMID:20165586Objectives: To assess relevance of spot morning spot (SMS) method of smear microscopy in tuberculosis control by directly observed treatment short course (DOTS). Materials and Methods : Screening of smear microscopy results of 546 cases of pulmonary tuberculosis at our DOTS centre. Results: Among 546 cases, 82% had all three samples positive for AFB, 98% had either morning sample or spot and morning sample positive. 2% had second spot sample positive. Conclusion: Examination of third sample, especially second spot sample, does not add significantly to the diagnostic yield. Examination of one spot and early morning samples were able to correctly diagnose 98% cases. This has strong implications in DOTS strategies. |
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Significance of upper airway influence among patients of vocal cord dysfunction for its diagnosis: Role of impulse oscillometry |
p. 5 |
HS Hira, Anshu Singh DOI:10.4103/0970-2113.45197 PMID:20165587Background: To identify the patients of bronchial asthma (suspected or proven), not responding to optimal therapy, for the presence of vocal cord dysfunction (VCD) and to compare the diagnostic ability of flow volume (FV) loop and impulse oscillometry (IOS). Materials and Methods: Fifty one patients of suspected/proven bronchial asthma not responding to optimal therapy were included for the study. Each patient was subjected to both FV loop and IOS studies. Direct visualization of the vocal cords with flexible fiberoptic bronchoscope for the presence of inspiratory vocal cord adduction during quiet respiration, with speech, and while performing provocative maneuvers was carried out. All patients were subjected to simple pulmonary function tests and recording of FV loop. IOS was performed on each patient to look for the site of obstruction and upper airway influence. The observations of both FV loop and IO studies were compared. Results: Among 51 patients participated, 12 (23.53%) had bronchoscopical evidence of VCD and were labeled as VCD-positive group and rest 39 were designated VCD negative. No statistically significant difference in pulmonary function test (prereversibility) results between the VCD-positive and VCD-negative patients was found. Reversible airway obstruction was observed in 75% of the patients of VCD-positive group and 67.65% of the patients in the VCD-negative group. Only one patient in the VCD-positive and none in VCD-negative group had inspiratory limb flattening of FV loop. Upper airway influence was evident by IOS in 58.3% of patients in the VCD-positive group and in 15.4% of patients in the VCD-negative group. This difference was statistically significant (P < 0.005). Conclusion: VCD was a common finding in patients with symptoms suggestive of asthma and frequently coexists with asthma. IOS was found to be a useful screening test for VCD and was more sensitive than FV loop. |
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REVIEW ARTICLES |
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Tuberculosis and nutrition  |
p. 9 |
Krishna Bihari Gupta, Rajesh Gupta, Atulya Atreja, Manish Verma, Suman Vishvkarma DOI:10.4103/0970-2113.45198 PMID:20165588Malnutrition and tuberculosis are both problems of considerable magnitude in most of the underdeveloped regions of the world. These two problems tend to interact with each other. Tuberculosis mortality rates in different economic groups in a community tend to vary inversely with their economic levels. Similarly, nutritional status is significantly lower in patients with active tuberculosis compared with healthy controls. Malnutrition can lead to secondary immunodeficiency that increases the host's susceptibility to infection. In patients with tuberculosis, it leads to reduction in appetite, nutrient malabsorption, micronutrient malabsorption, and altered metabolism leading to wasting. Both, protein-energy malnutrition and micronutrients deficiencies increase the risk of tuberculosis. It has been found that malnourished tuberculosis patients have delayed recovery and higher mortality rates than well-nourished patients. Nutritional status of patients improves during tuberculosis chemotherapy. High prevalence of human immunodeficiency (HIV) infection in the underdeveloped countries further aggravates the problem of malnutrition and tuberculosis. Effect of malnutrition on childhood tuberculosis and tuberculin skin test are other important considerations. Nutritional supplementation may represent a novel approach for fast recovery in tuberculosis patients. In addition, raising nutritional status of population may prove to be an effective measure to control tuberculosis in underdeveloped areas of world. |
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Endobronchial ultrasound: A new innovation in bronchoscopy |
p. 17 |
T Balamugesh, FJ Herth DOI:10.4103/0970-2113.45199 PMID:20165589Technical development in last two decades has made it possible for pulmonologists to do endobronchial ultrasound (EBUS). With EBUS mini-probe, the multilayered structure of the tracheobronchial wall can be analyzed better than any other imaging modality. Instead of fluoroscopic guided biopsy, EBUS can be used to biopsy peripheral lesions. EBUS-transbronchial needle aspiration has proved valuable for mediastinal lymph node staging of lung cancer. Studies have shown that EBUS is cost-effective as it reduces the need for more morbid and costly invasive procedure like mediastinoscopy or thoracotomy. Prospective studies are needed in India to see how EBUS will help in populations with high prevalence of tuberculosis. |
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CASE REPORTS |
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Tuberculous otitis media with postaural abscess and submandibular lymphadenopathy |
p. 22 |
Sanjeev K Verma, Vineet Mahajan, Anand N Srivastava DOI:10.4103/0970-2113.45200 PMID:20165590We are reporting a case of right-sided tuberculous otitis media with postaural abscess and multiple submandibular lymphadenopathy which has been reported very infrequently. A high level of suspicion by the treating physician is mandatory to avoid long delay in diagnosis and increased complications in the modern chemotherapy era. |
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Acquired bronchoesophageal fistula |
p. 24 |
Deepak Aggarwal, Prasanta Raghab Mohapatra, Balbir Malhotra DOI:10.4103/0970-2113.45201 PMID:20165591Bronchoesophageal fistula in an adult is rarely encountered in clinical practice. Most commonly, they have malignant origin. We report a case of bronchoesophageal fistula secondary to trauma caused by upper gastrointestinal endoscopy. The patient presented with recurrent chest infections and dysphagia since he underwent endoscopic procedure for obstructed denture. Barium swallow study revealed fistulous connection between right lower lobe bronchus and esophagus. |
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Scimitar syndrome: A rare disease with unusual presentation |
p. 26 |
Manohar Lal Gupta, Rajeev Bagarhatta, Jyotsna Sinha DOI:10.4103/0970-2113.45202 PMID:20165592Scimitar syndrome is a rare congenital disorder. It has a varied presentation. In adult life, it usually presents either as recurrent chest infection and/or exertional dyspnea. Pulmonary artery hypertension and hemoptysis both are uncommon features of this syndrome in adult life. |
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BOOK REVIEW |
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World's super scientists |
p. 30 |
SK Jindal |
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