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Official publication of Indian Chest Society
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1999| July-September | Volume 17 | Issue 3
Online since
January 5, 2011
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Role Of Glutathione-S-Transferase In Smoking Induced Lung Diseases
R Gupta, B Raj, J Saini, A. K Janmeja
July-September 1999, 17(3):84-87
The present study was undertaken to study the status of glutathione-S-transferase (GST) in bronchoalveolar lavage fluid (BALF) in patients of primary pulmonary malignancies and chronic bronchitis using fiberoptic bronchoscope. GST activity was estimated by Habig method in fifteen patients with primary pulmonary malignancy and fifteen patients with chronic bronchitis. Mean GST activity in BAL samples of cases of primary pulmonary malignancy was 0.207+0.1015 i.u./mg of proteins whereas it was only 0.0723 + 0.0156i.u./mg. of proteins in cases of chronic bronchitis. The mean GST activity in BAL samples of primary pulmonary malignancy was significantly higher as compared to chronic bronchitis (pc 0.001). More than 85% of the patients of primary pulmonary malignancy had GST activity more than 0.100 i.u./mg of proteins in their BAL samples whereas only in one patient (6.67%) of chronic bronchitis, GST activity was more than 0.101 i.u./mg of proteins. The GST activity in serum was very low with insignificant change in two groups and in different patients.
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Co-Existent Malignant Lymphoma And Tubercular Lymphadenitis - A Case Report
O. P Gupta, R Gupta, V. K Arora
July-September 1999, 17(3):95-97
A case of 55 years man with tubercular Lymphadenitis and co-existent lymphoma is reported. Chronic inflammation of tuberculosis or specific drug exposure could be important factors in inducing p53 mutations or any other chromosomal abnormalities or oncogene production leading to lymphomagenesis. Though exact mechanism of the co-existence of both the diseases remain unknown, some genetic alteration linking the two seems to be the most favourable hypothesis.
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Pulmonary Geiotrichosis : A Rare Mycotic Infection
Dinesh Gohel, V. C Poria, B. M Kikani, K. J Upadhayay
July-September 1999, 17(3):98-99
We report one of the established but extremely rare type of mycoses in a male patient having fibrocavitary pulmonary tuberculosis, who presented with cough, mucoid sputum and mild haemoptysis. His X ray chest revealed a fungal ball in a cavity. Geiotrichum candidum was isolated from multiple specimens of freshly expectorated suputum and from fine needle aspiration specimen and he responded to ketoconazole therapy.
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Comparative Efficacy And Safety Of Inhaled Glucocorticoids In The Treatment Of Adult Bronchial Asthma : A Review
Ashuthosh Nath Aggarwal, Dheeraj Gupta
July-September 1999, 17(3):88-92
We briefly review the pharmacology, efficacy and safety of inhaled fluticasone propionate in the management of bronchial asthma in adults and compare this drug with other inhaled glucocorticoids available in India.
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Directly Observed Therapy - Short Course (DOTs)
K. C Mohanty
July-September 1999, 17(3):82-83
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Young's Syndrome : Report Of Two Cases
S. K Banerjee, S Bhatt, J. M Joshi
July-September 1999, 17(3):93-94
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High Resolution CT Appearance Of Diffuse Amyloidosis
D. V Sahani, M Ruparel, P. G Shetty, Z. F Udwadia
July-September 1999, 17(3):100-101
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